With Peter Dimov's help I've resolved my earlier problems packaging Boost for Fedora. Now my problem is that the generated .cmake files contain the full --prefix path, which is not what I want because that's just a staging area, not the final resting place for the files (think DESTDIR in an autotools build). I see lines like this in each of the installed .cmake files: /builddir/build/BUILDROOT/boost-1.73.0-0.1.fc33.x86_64/usr/lib64/openmpi/lib/cmake/boost_python-1.73.0/boost_python-config.cmake:if(EXISTS "/builddir/build/BUILDROOT/boost-1.73.0-0.1.fc33.x86_64/usr/lib64/openmpi/lib/cmake") /builddir/build/BUILDROOT/boost-1.73.0-0.1.fc33.x86_64/usr/lib64/openmpi/lib/cmake/boost_python-1.73.0/boost_python-config.cmake: get_filename_component(_BOOST_CMAKEDIR_ORIGINAL "/builddir/build/BUILDROOT/boost-1.73.0-0.1.fc33.x86_64/usr/lib64/openmpi/lib/cmake" REALPATH) /builddir/build/BUILDROOT/boost-1.73.0-0.1.fc33.x86_64/usr/lib64/openmpi/lib/cmake/boost_python-1.73.0/boost_python-config.cmake: set(_BOOST_CMAKEDIR "/builddir/build/BUILDROOT/boost-1.73.0-0.1.fc33.x86_64/usr/lib64/openmpi/lib/cmake") These files won't work after everything gets moved from the staging area $RPM_BUILD_ROOT/usr/... to the final lcoation on a user's machine, under /usr/... I can just use sed to alter them, but surely there's way to set the desired prefix? I'm trying: ./bootstrap.sh --with-toolset=gcc --with-icu --prefix=/usr ./b2 -d+2 -q -j 4 \ --without-mpi --without-graph_parallel --build-dir=serial \ --prefix=/usr --libdir=/usr/lib64 \ variant=release threading=multi debug-symbols=on pch=off \ python=3.8 \ stage ... ./b2 -d+2 -q -j 4 \ --without-mpi --without-graph_parallel --build-dir=serial \ --prefix=$RPM_BUILD_ROOT/usr \ --libdir=$RPM_BUILD_ROOT/usr/lib64 \ variant=release threading=multi debug-symbols=on pch=off \ python=%{python3_version} \ install And this produces the .cmake files with the unwanted $RPM_BUILD_ROOT/usr prefixes. I originally didn't have the --prefix and --libdir options on the bootstrap.sh command and the 'b2 .. . stage' command, but it doesn't seem to matter whether they're there or not. Is there some way to control the prefix that ends up in those .cmake files?